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Relative expression of PTTG and bFGF in oral squamous cell carcinoma and Tca8113

Yumei DING BM , Lili CHEN MD , Bo CHENG PhD , Handong ZHANG MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 357-362 doi: 10.1007/s11684-009-0046-1

Abstract: expression of pituitary tumor transforming gene (PTTG) and basic fibroblast growth factor (bFGF) in oralsquamous cell carcinoma (OSCC) and tongue cancer cell line Tca8113, as well as their effects on each

Keywords： carcinoma     squamous cell     pituitary tumor transforming gene (PTTG) protein     basic fibroblast growth factor    

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Factors related to compliance with oral analgesic treatment of inpatients with chronic pain

Hong Zhu,Yuzhu Zheng,Hui Gao,Li Liu,Lie Yang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 374-379 doi: 10.1007/s11684-015-0411-1

Abstract: investigated 100 consecutive inpatients with non-cancer chronic pain who were hospitalized to receive oral, 95%CI: 1.03–3.31, P=0.016) were associated with moderate or non-compliance with oralIn conclusion, the low compliance with oral treatment of analgesics was found in Chinese inpatients with

Keywords： chronic pain     inpatient     oral paregoric drugs     compliance    

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Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new co-clinical model for treatment optimization

Shuyang Sun,Zhiyuan Zhang

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 104-110 doi: 10.1007/s11684-016-0432-4

Abstract: bioinformatics have begun to reveal the complex genetic landscape in human cancer genomes, including oralsquamous cell carcinoma (OSCC).

Keywords： patient-derived xenograft models     personalized medicine     co-clinical trial     patient stratification     oralsquamous cell carcinoma    

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Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4,   Pages 516-520 doi: 10.1007/s11705-017-1658-7

Abstract: products are formulated with a drug, an active ingredient to produce the maximum therapeutic effect after oralorder to assure the safety and efficacy of pharmaceutical products, we need an predictive tool for oralOral immediate release (IR) dosage forms cannot be optimal for all drugs or likely even any drugs (APIsBut how do we optimize oral delivery of drugs? It is usually through ‘trial and error’, in humans!We need a better way to optimize the oral dosage forms.

Keywords： GIS     in vivo predictive dissolution     ketoconazole     BCS subclassification     supersaturation    

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Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 401-413 doi: 10.1007/s11684-011-0161-7

Abstract: preclinical animal models for bone regeneration and the key translational points to clinical success in oralstrategies based on stem cell and tissue engineering researches, allowing for clinical application in oral

Keywords： bone regeneration     animal models     translational strategies     oral and maxillofacial region    

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Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 9-19 doi: 10.1007/s11705-013-1306-9

Abstract: Oral insulin delivery has received the most attention in insulin formulations due to its high patientHowever, oral insulin delivery has two major limitations: the enzymatic barrier that leads to rapid insulinmajor success in overcoming the mucosal barrier, which is the main cause in undercutting insulin’s oralIn this review of our group’s research, an innovative silica-based, mucoadhesive oral insulin formulationbarriers is discussed, and the preliminary and convincing results to confirm the plausibility of this oral

Keywords： insulin     cell penetrating peptide     mucoadhesive composites     oral delivery    

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Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 815-826 doi: 10.1007/s11684-021-0891-0

Abstract: Oral drugs such as ibrutinib play an important role in the treatment of mature B-cell lymphoma (BCL)Still, no guidelines or consensus focusing on oral drug therapies for BCL is available.Hematology, Chinese Medical Association conducted an extensive discussion and reached a consensus on oraldrugs for Chinese BCL patients on the basis of the current application status of oral drugs in ChinaThis consensus reviewed the application of oral drugs in the treatment of BCL and the latest research

Keywords： B-cell lymphoma     oral drug     targeted therapy     immunotherapy     COVID-19 pandemic    

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Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma and

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 132-142 doi: 10.1007/s11684-022-0938-x

Abstract: Nasopharyngeal carcinoma (NPC) is a malignant tumor that mainly occurs in East and Southeast Asia.

Keywords： nasopharyngeal carcinoma     WGCNA     RFC4     proliferation    

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Meta-analysis of the risk factors of breast cancer concerning reproductive factors and oral contraceptive

Qiong DAI MD, Bei LIU MD, Yukai DU MM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 452-458 doi: 10.1007/s11684-009-0080-z

Abstract: authors performed a meta-analysis of case-control studies that addressed whether reproductive factors and oralmenopausal age >50yr [odds ratio (OR), 1.39; 95% confidence interval (CI), 1.22―1.57] and oralMenopausal age >50yr and oral contraceptive use are positively correlated with an increase

Keywords： meta-analysis     breast cancer     risk factors     reproductive factors     oral contraceptive use    

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A Double-Layer Polysaccharide Hydrogel (DPH) for the Enhanced Intestine-Targeted Oral Delivery of Probiotics

Wen-Can Huang,Wenjie Wang,Wei Wang,Yanan Hao,Changhu Xue,Xiangzhao Mao,

Engineering doi: 10.1016/j.eng.2023.05.024

Abstract: Thus, DPH endows probiotics with excellent intestine-targeted delivery, improved oral bioavailabilityexhibit almost unchanged bioactivity in the gastrointestinal tract before release, as well as improved oral

Keywords： Polysaccharides     Chitosan     Hydrogels     Oral delivery     Intestine-targeted    

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The impact of hypoxia in hepatocellular carcinoma metastasis

Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Irene Oi-Lin Ng

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 33-41 doi: 10.1007/s11684-013-0301-3

Abstract:

Hypoxia is a common phenomenon in hepatocellular carcinoma (HCC).

Keywords： hypoxia     hepatocellular carcinoma (HCC)     metastasis     hypoxia-inducible factor (HIF)    

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Oral administration of

Sufen ZHAO,Yuanyuan JIA,Weiwei ZHANG,Lili WANG,Yunfei MA,Kedao TENG

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 4,   Pages 318-326 doi: 10.15302/J-FASE-2015080

Abstract: The effects of oral administration of garlic mixture (GM, water-soluble extract) on infectious bursalThe results confirmed the protective effects of oral administration of 5 mg·kg BW GM (Group GM1) onsignificantly increased 7 days post infection in bursae in Group GM1 ( <0.01), suggesting that the oral

Keywords： garlic     infectious bursal disease virus (IBDV)     antiviral effect     IgM-bearing B lymphocyte    

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Osteopontin is a promoter for hepatocellular carcinoma metastasis: a summary of 10 years of studies

Lunxiu Qin

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 24-32 doi: 10.1007/s11684-014-0312-8

Abstract: study, OPN was identified as one of the leading genes associated with the metastasis of hepatocellular carcinoma

Keywords： osteopontin (OPN)     hepatocellular carcinoma     metastasis     prognosis     therapeutic target     biomarker     genetic    

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Natural killer cells in hepatocellular carcinoma: current status and perspectives for future immunotherapeutic

Min Yu, Zonghai Li

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 509-521 doi: 10.1007/s11684-017-0546-3

Abstract:

Hepatocellular carcinoma (HCC) is currently the fifth most common malignancy and the third leading

Keywords： natural killer cell     hepatocellular carcinoma     immunotherapy    

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Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 191-202 doi: 10.1007/s11684-017-0512-0

Abstract:

Primary hepatic carcinoma (PHC) is a common malignant tumor in China.with meta-analysis aimed to assess the effect of TCM combined with Western therapy on primary hepatic carcinoma

Keywords： traditional Chinese medicine     primary hepatic carcinoma     meta-analysis    

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Title Author Date Type Operation

Relative expression of PTTG and bFGF in oral squamous cell carcinoma and Tca8113

Yumei DING BM , Lili CHEN MD , Bo CHENG PhD , Handong ZHANG MM ,

Journal Article

Factors related to compliance with oral analgesic treatment of inpatients with chronic pain

Hong Zhu,Yuzhu Zheng,Hui Gao,Li Liu,Lie Yang

Journal Article

Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new co-clinical model for treatment optimization

Shuyang Sun,Zhiyuan Zhang

Journal Article

Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

Journal Article

Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Journal Article

Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Journal Article

Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)

Journal Article

Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma and

Journal Article

Meta-analysis of the risk factors of breast cancer concerning reproductive factors and oral contraceptive

Qiong DAI MD, Bei LIU MD, Yukai DU MM,

Journal Article

A Double-Layer Polysaccharide Hydrogel (DPH) for the Enhanced Intestine-Targeted Oral Delivery of Probiotics

Wen-Can Huang,Wenjie Wang,Wei Wang,Yanan Hao,Changhu Xue,Xiangzhao Mao,

Journal Article

The impact of hypoxia in hepatocellular carcinoma metastasis

Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Irene Oi-Lin Ng

Journal Article

Oral administration of

Sufen ZHAO,Yuanyuan JIA,Weiwei ZHANG,Lili WANG,Yunfei MA,Kedao TENG

Journal Article

Osteopontin is a promoter for hepatocellular carcinoma metastasis: a summary of 10 years of studies

Lunxiu Qin

Journal Article

Natural killer cells in hepatocellular carcinoma: current status and perspectives for future immunotherapeutic

Min Yu, Zonghai Li

Journal Article

Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Journal Article